update data_curated

downloads-generation/data_curated/curate.py

@@ -56,7 +56,7 @@ parser.add_argument(
 
 QUALITATIVE_TO_AFFINITY_AND_INEQUALITY = {
     "Negative": (5000.0, ">"),
-    "Positive": (500.0, "<"),  # used for mass-spec hits
+    "Positive": (50.0, "<"),  # used for mass-spec hits
     "Positive-High": (100.0, "<"),
     "Positive-Intermediate": (1000.0, "<"),
     "Positive-Low": (5000.0, "<"),

downloads-generation/models_class1_pan/generate_hyperparameters.py

@@ -36,7 +36,7 @@ base_hyperparameters = {
     'peptide_amino_acid_encoding': 'BLOSUM62',
     'peptide_dense_layer_sizes': [],
     'random_negative_affinity_max': 50000.0,
-    'random_negative_affinity_min': 20000.0,
+    'random_negative_affinity_min': 35000.0,
     'random_negative_constant': 1,
     'random_negative_distribution_smoothing': 0.0,
     'random_negative_match_distribution': True,

mhcflurry/downloads.yml

@@ -83,7 +83,7 @@ releases:
               default: false
 
             - name: data_curated
-              url: https://github.com/openvax/mhcflurry/releases/download/1.4.0/data_curated.20200101.tar.bz2
+              url: https://github.com/openvax/mhcflurry/releases/download/1.6.0/data_curated.20200103.tar.bz2
               default: true
 
             # Older downloads